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Real Betis vs Real Madrid Prediction: Los Blancos Aim to Keep Pace

The stage is set for an enthralling La Liga clash as Real Betis welcome Real Madrid to the Estadio Benito Villamarín on Friday, September 4, 2026, at 19:00 UTC. This Regular Season – 4 fixture promises high stakes, with Madrid aiming to maintain their perfect start and Betis looking to bounce back from recent setbacks.

Form Guide

Real Betis have had a mixed run of form lately, with their last five matches resulting in two wins and three losses. They’ve averaged 1.3 goals per game but conceded 1.7, highlighting defensive vulnerabilities. In contrast, Real Madrid have been in imperious form, winning all their last five matches while scoring an average of 3.3 goals per game and conceding just 0.7. Their attacking prowess and defensive solidity make them formidable opponents.

Head-to-Head

The recent history between these two sides has been dramatic, with Madrid often dominating but Betis occasionally springing surprises. Their last encounter on April 24, 2026, ended in a 1-1 draw, while earlier in the season, Madrid thrashed Betis 5-1 at home. Betis’ last victory came on March 1, 2025, with a 2-1 win, showcasing their ability to rise to the occasion.

Team News & Injuries

Betis face significant challenges with key players sidelined. Midfield maestro Gio Lo Celso is out with a muscle injury, while Ayoub Ezzalzouli is ill. Defensive concerns are compounded by the absences of Dani Conde and Aitor Ruibal due to shoulder and knee injuries, respectively. Meanwhile, Real Madrid’s squad depth is tested with injuries to Rodrygo, Eder Militao, and Endrick, among others. These absences could impact Madrid’s fluidity but their bench remains stacked with talent.

The Odds

According to 10Bet, Real Madrid are heavy favourites with odds of 1.40, while Betis sit at 6.40 for a win. The draw is priced at 5.10, with odds of 1.38 suggesting a high likelihood of over 2.5 goals in the match.

Our Prediction

With Madrid’s superior form and attacking firepower, they are tipped to edge this encounter. Despite Betis’ resilience, the absence of key players tilts the balance in Madrid’s favour. Our prediction: Real Betis 1-3 Real Madrid.

Odds are informational, correct at time of publishing and subject to change. 18+, please gamble responsibly.